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As data on the chronic use of sevelamer for over one year are not yet availablepotential absorption and accumulation of sevelamer during long-term chronic treatment cannot be totally excludedsee section 5.2
Patients with long-term kidney disease cannot eliminate phosphate from their bodiesThis leads to hyperphosphataemiawhichin the long termcan cause complications such as heart and bone diseaseThe active substance in Renagelsevelamer hydrochlorideis a phosphate binderWhen taken with mealsit attaches to phosphate from food within the gutpreventing it from being absorbed into the bodyThis helps to reduce the phosphate levels in the blood.
Because clinical trials are conducted under widely varying conditionsadverse reaction rates observed cheap yougaramdewbaba in the clinical trials of a drug can not be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
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